Search all Port Charlotte homes for sale & real estate in Port Charlotte, FL. Further down this page find all Port Charlotte Florida real estate listings that are continuously updated. Port Charlotte is located on Florida's Gulf Coast of Mexico and about half way between Sarasota and Fort Myers. Port Charlotte is directly on Charlotte Harbor and features more than 165 miles of waterways and miles of natural shoreline bordering Charlotte Harbor and the Peach and Myakka rivers. There is lots to do in Port Charlotte including seven golf courses of different challenge levels, world class fishing and boating, fabulous shopping and dining, state of the art medical facilities, Sunseeker Resort to be completed 2023, Charlotte Sports Park is home to spring training for the Tampa Bay Rays and many parks offering hiking trails, boat launches and wildlife viewing.